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Tubulin/HDAC-IN-4
GENERAL CATALOGUE

Tubulin/HDAC-IN-4

HY-162319 · 50 mg

MedChemExpress · Cat: HY-162319

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Catalog No: HY-162319
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

Tubulin/HDAC-IN-4 compound 9n is a dual Tubulin and HDAC inhibitor with IC50 values of 0.73, 0.43, 0.62, 2.34 AAasAasAAmuM for HDAC1, HDAC2, HDAC6, HDAC7, respectively. Tubulin/HDAC-IN-4 inhibits the tubulin polymerization by targeting the colchicine binding site. Tubulin/HDAC-IN-4 induces apoptosis and cell cycle arrest at G2/M phase. Tubulin/HDAC-IN-4 induces a significant elevation of intracellular ROS levels. Tubulin/HDAC-IN-4 shows anti-angiogenesis activity and anticancer activity.

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