

HY-157165 · 50 mg
MedChemExpress · Cat: HY-157165
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Manufacturer product page
medchemexpress.com/tubulin-parp-in-1.html
Description
Tubulin/PARP-IN-1 compound 14 is a dual PARP-tubulin inhibitor with activity against endometrial cancer. Tubulin/PARP-IN-1 inhibits PARP and tubulin with IC50s of 74 nM PARP1 , 109 nM PARP2 , and 1.4 ?M Microtubule/Tubulin , respectively. Tubulin/PARP-IN-1 can induce apoptosis and autophagy and cause cell cycle arrest in the G2/M phase.





