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Tubulin/PARP-IN-1
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Tubulin/PARP-IN-1

HY-157165 · 50 mg

MedChemExpress · Cat: HY-157165

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Catalog No: HY-157165
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

Tubulin/PARP-IN-1 compound 14 is a dual PARP-tubulin inhibitor with activity against endometrial cancer. Tubulin/PARP-IN-1 inhibits PARP and tubulin with IC50s of 74 nM PARP1 , 109 nM PARP2 , and 1.4 ?M Microtubule/Tubulin , respectively. Tubulin/PARP-IN-1 can induce apoptosis and autophagy and cause cell cycle arrest in the G2/M phase.

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