GENERAL CATALOGUE
?-Tubulin polymerization-IN-1
HY-173039 · 50 mg
MedChemExpress · Cat: HY-173039
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medchemexpress.com/%CE%B1-tubulin-polymerization-in-1.htmlCatalog No: HY-173039
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
?-Tubulin polymerization-IN-1 Compound 8l is an inhibitor for ?-Tubulin polymerization. ?-Tubulin polymerization-IN-1 modulates the NRF2/KEAP-1 signaling pathway, induces ROS generation in PC-3 cell, thereby inducing apoptosis in PC-3. ?-Tubulin polymerization-IN-1 inhibits the proliferation of PC-3 cell with a GI50 of 0.17 AAasAasAAmuM, arrests the cell cycle at G2/M phase. ?-Tubulin polymerization-IN-1 exhibits antitumor efficacy in mouse model.
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