GENERAL CATALOGUE
Tubulin polymerization-IN-59
HY-157543 · 5 mg
MedChemExpress · Cat: HY-157543
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medchemexpress.com/tubulin-polymerization-in-59.htmlCatalog No: HY-157543
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
Tubulin polymerization-IN-59 is a tubulin polymerization inhibitor and colchicine binding site inhibitor CBSI IC50 = 6.1 ?M . Tubulin polymerization-IN-59 exerts potent antiproliferative activity against cancer cells, while showing lower cytotoxicity to normal cells. Tubulin polymerization-IN-59 arrests colorectal cancer HCT 116 cells in G2/M phase, induces cell apoptosis, and suppresses tumor cell colony formation and migration. Tubulin polymerization-IN-59 can be used for the study of colorectal cancer CRC .