

HY-163983 · 50 mg
MedChemExpress · Cat: HY-163983
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medchemexpress.com/tubulin-polymerization-in-68.htmlDescription
Tubulin polymerization-IN-68 compound 32 is a tubulin inhibitor that can inhibit tubulin polymerization and destroy the cellular microtubule network. Tubulin polymerization-IN-68 can upregulate the expression of PARP-1 and caspase-3 and induce cell apoptosis, and has anticancer activity. Tubulin polymerization-IN-68 can effectively inhibit HepG2 IC50=93 nM and significantly inhibit the growth of HepG2 xenograft tumors in nude mice by oral administration.







