Tubulysin A intermediate-1

Description

Tubulysin A intermediate-1 is an intermediate in the synthesis of the cytotoxic peptide Tubulysin A HY-15995 . Tubulysin A TubA is an antibiotic, anti-microtubule toxins, and apoptosis inducer isolated from myxobacteria. Tubulysin A has anti-angiogenic, anti-microtubule, anti-mitotic, and anti-proliferative activities. Tubulysin A arrests cells in the G2/M phase, effectively inhibits tubulin polymerization, and induces depolymerization of detached microtubules. Tubulysin A acts as an ADC cytotoxin ADC Cytotoxin to synthesize ADC.