GENERAL CATALOGUE
Tubulysin D
HY-N2348 · 5 mg
MedChemExpress · Cat: HY-N2348
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medchemexpress.com/tubulysin-d.htmlCatalog No: HY-N2348
CAS No: 309935-57-7
Category: Antibody-drug Conjugate ADC Related
Pack Size: 5 mg
Brand: MedChemExpress
Description
Tubulysin D is a highly cytotoxic anti-microtubule toxin anti-microtubule toxins that is synthesized as an ADC cytotoxin ADC Cytotoxin . Tubulysin D can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin D displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin D inhibits microtubule/Tubulin polymerization and leads to cell cycle arrest and apoptosis.
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