GENERAL CATALOGUE
Tubulysin I
HY-N7052 · 5 mg
MedChemExpress · Cat: HY-N7052
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Catalog No: HY-N7052
CAS No: 799822-10-9
Category: Antibody-drug Conjugate ADC Related
Pack Size: 5 mg
Brand: MedChemExpress
Description
Tubulysin I is a highly cytotoxic anti-microtubule toxin anti-microtubule toxins that is synthesized as an ADC cytotoxin ADC Cytotoxin . Tubulysin I can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin I displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin I inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis.
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