GENERAL CATALOGUE
TUG-424
HY-14363 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-14363
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Catalog No: HY-14363
CAS No: 1082058-99-8
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
TUG-424 is a potent and selective free fatty acid receptor 1 FFA1/GPR40 agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity. TUG-424 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing Azide groups.
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