GENERAL CATALOGUE
Tuxobertinib
HY-136789 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-136789
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Manufacturer product page
medchemexpress.com/bdtx-189.htmlCatalog No: HY-136789
CAS No: 2414572-47-5
Category: JAK STAT Signaling
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Tuxobertinib BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, including EGFR/HER2 exon 20 insertion mutants. Tuxobertinib shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity.
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