GENERAL CATALOGUE
TX-2552
HY-161853 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-161853
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Catalog No: HY-161853
CAS No: 2446767-14-0
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
TX-2552 is an orally active tyrosine DNA phosphodiesterase 1 TDP1 inhibitor with an IC50 value of 0.62 ?M. TX-2552 can enhance the clastogenic activity of Topotecan HY-13768 in mouse bone marrow cells, as well as the anti-tumor effect of Topotecan HY-13768 in Krebs-2 ascites tumor mice.
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