GENERAL CATALOGUE
TX1-85-1
HY-100848 · 1 mg
MedChemExpress · Cat: HY-100848
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Manufacturer product page
medchemexpress.com/tx1-85-1.htmlCatalog No: HY-100848
CAS No: 1603845-32-4
Category: JAK STAT Signaling
Pack Size: 1 mg
Brand: MedChemExpress
Description
TX1-85-1 is an irreversible Her3 ErbB3 inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling.
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