GENERAL CATALOGUE
TX2-121-1
HY-118998 · 50 mg
MedChemExpress · Cat: HY-118998
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medchemexpress.com/tx2-121-1.html
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Catalog No: HY-118998
CAS No: 1603845-42-6
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
TX2-121-1 is a potent and selective Her3 ErbB3 degrader that contains a hydrophobic adamantane moiety. TX2-121-1 has an IC50 of 49 nM for Her3. TX2-121-1 inhibits Her3-dependent signaling and heterodimerization of Her3. TX2-121-1 has the ability to inhibit cell proliferation. TX2-121-1 can be used in the study of tumors. Pink: Her3 inhibitor HY-164988 ; Black: Linker; Blue: Adamantane HY-N2427 .
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