GENERAL CATALOGUE
Tyroserleutide hydrochloride
HY-106263B · 5 mg
MedChemExpress · Cat: HY-106263B
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Manufacturer product page
medchemexpress.com/tyroserleutide-hydrochloride.htmlCatalog No: HY-106263B
CAS No: 852982-42-4
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Tyroserleutide hydrochloride is a tripeptide isolated from the degradation products of porcine spleen with antitumor activity. Tyroserleutide hydrochloride can upregulate the expression of the tumor suppressor gene PTEN and inhibit the activity of AKT and PDK1. Tyroserleutide hydrochloride inhibits tumor cell proliferation and MDM2 phosphorylation by inhibiting the PI3K/AKT pathway, and also upregulates P21, P27, P53, and induces mitochondrial damage and cell apoptosis.
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