GENERAL CATALOGUE
U-99194
HY-12701 · 50 mg
MedChemExpress · Cat: HY-12701
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medchemexpress.com/u-99194.htmlCatalog No: HY-12701
CAS No: 82668-33-5
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
U-99194 PNU-99194 is a selective, potent dopamine D3 receptor antagonist. U-99194 inhibits the activation of D3 receptor mediated by endogenously released dopamine or exogenous D3 agonists. U-99194 abrogates the IPSC-suppressive effect of the D3 agonist PD 128907 in rat hippocampal slices. U-99194 significantly suppresses Nicotine HY-127019 -induced tremor in mice. U-99194 can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.
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