GENERAL CATALOGUE
U-99194 maleate
HY-12701A · 5 mg
MedChemExpress · Cat: HY-12701A
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medchemexpress.com/u-99194-maleate.htmlCatalog No: HY-12701A
CAS No: 234757-41-6
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
U-99194 PNU-99194 maleate is a selective, potent dopamine D3 receptor antagonist Ki =160 nM . U-99194 maleate inhibits the activation of D3 receptor mediated by endogenously released dopamine or exogenous D3 agonists. U-99194 maleate abrogates the IPSC-suppressive effect of the D3 agonist PD 128907 in rat hippocampal slices. U-99194 maleate significantly suppresses Nicotine HY-127019 -induced tremor in mice. U-99194 maleate can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.
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