U937 Stably Expressing Wild-type SAMHD1 Cell Line

Description

Sterile alpha motif and HD domain-containing protein 1 SAMHD1 is a deoxynucleoside triphosphohydrolase dNTPase with a nuclear localization signal NLS . This cell line is one of three cell lines expressing either the wild-type SAMHD1 or the mutant variants: defective in dNTPase activity HD/RN or nuclear localization mNLS . These cell lines are suitable for studies investigating the role and mechanisms of SAMHD1 in suppressing innate immunity. Cell lines part of this group: Cat. T3222 - U937 Stably Expressing Wild-type SAMHD1 Cell Line Cat. T3323 - U937 Stably Expressing SAMHD1 Mutant HD/RN Cell Line Cat. T3324 - U937 Stably Expressing mutant NLS Cell Line