UBE3C Rabbit Polyclonal Antibody

Description

EnkiLife offers the UBE3C Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for WB,ELISA application. Alternative Names of Immunogen: UBE3C; KIAA0010; KIAA10; Ubiquitin-protein ligase E3C; HectH2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:5000-1:20000 Background: function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. miscellaneous:A cysteine residue is required for ubiquitin-thioester formation. pathway:Protein modification; protein ubiquitination. similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. similarity:Contains 1 IQ domain. subunit:Interacts with 26S proteasomes. Binds CAND2. tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas. Research Area:Ubiquitin mediated proteolysis;