GENERAL CATALOGUE
UMI-77
HY-18628 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-18628
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Manufacturer product page
medchemexpress.com/UMI-77.htmlCatalog No: HY-18628
CAS No: 518303-20-3
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 IC50=0.31 ?M . UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
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