GENERAL CATALOGUE
UNC-2170
HY-115531 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-115531
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Catalog No: HY-115531
CAS No: 1648707-58-7
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
UNC-2170 is a functionally active, fragment-like ligand for 53BP1 IC50=29 AAasAasAAmuM; Kd=22 AAasAasAAmuM . UNC-2170 shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine Kme reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair DDR pathways and is recruited to sites of double-strand breaks DSB .
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