GENERAL CATALOGUE
UNC0638
HY-15273 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-15273
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Catalog No: HY-15273
CAS No: 1255580-76-7
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
UNC0638, a chemical probe, selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 inhibits TNBC cell invasion and migration in vitro. UNC0638 is also an inhibitor of EHMT1/2 and induces fetal hemoglobin HbF expression in human erythroid progenitor cell culture. In addition, UNC0638 has anti-FMDV foot-and-mouth disease virus and anti-VSV vesicular stomatitis virus activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets.
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