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UNC0638 hydrate
GENERAL CATALOGUE

UNC0638 hydrate

HY-110093 · 50 mg

MedChemExpress · Cat: HY-110093

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Catalog No: HY-110093
CAS No: 1255517-77-1
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 hydrate inhibits TNBC cell invasion and migration in vitro. UNC0638 hydrate is also an inhibitor of EHMT1/2 and induces fetal hemoglobin HbF expression in human erythroid progenitor cell culture. In addition, UNC0638 hydrate has anti-FMDV foot-and-mouth disease virus and anti-VSV vesicular stomatitis virus activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets.

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