GENERAL CATALOGUE
UNC0646
HY-13807 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13807
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Catalog No: HY-13807
CAS No: 1320288-17-2
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
UNC0646 is a potent and selective histone methyltransferase G9a inhibitor with an IC50 of 6 nM. UNC0646 is also a potent GLP inhibitor IC50 <15 nM and highly selective for G9a/GLP over SETD7, SUV39H2, SETD8 and PRMT3. UNC0646 reduces H3K9me2 levels in MDA-MB-231 cells with an IC50 of 26 nM.
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