GENERAL CATALOGUE
UNC3474
HY-156906 · 5 mg
MedChemExpress · Cat: HY-156906
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Catalog No: HY-156906
CAS No: 1648707-79-2
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
UNC3474 is a small molecule ligand, binding with 53BP1. UNC3474 binds the aromatic methyl-lysine binding cage of 53BP1TT, with a dissociation constant Kd of 1.0?AAasAasAA+/-?0.3 ?M. UNC3474 inhibits the recruitment of 53BP1 to DSBs by stabilizing a pre-existing autoinhibited state of 53BP1 in cells.
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