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UNC6535
GENERAL CATALOGUE

UNC6535

HY-168992 · 50 mg

MedChemExpress · Cat: HY-168992

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medchemexpress.com/unc6535.html
Catalog No: HY-168992
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

UNC6535 is a potent and reversible SETDB1 triple Tudor domain 3TD ligand, with an IC50 of 3.4 AAasAasAAmuM. UNC6535 occupies simultaneously both the TD2 and TD3 reader binding sites. UNC6535 weakly inhibits SETDB1 methyltransferase activity, with an IC50 of 84 AAasAasAAmuM for the full-length protein. UNC6535 lacks selectivity for the 3TD and may also interact with the SET domain.

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