GENERAL CATALOGUE
Upacicalcet sodium
HY-109106A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-109106A
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Catalog No: HY-109106A
CAS No: 2052969-18-1
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist EC50 = 10.8 nM . Upacicalcet sodium reduces serum intact parathyroid hormone iPTH and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine HY-B0152 -induced secondary hyperparathyroidism SHPT rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease CKD . Upacicalcet sodium is useful for studying SHPT.
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