GENERAL CATALOGUE
Urocortin II, mouse
HY-P2847 · 1 mg
MedChemExpress · Cat: HY-P2847
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medchemexpress.com/urocortin-ii-mouse.htmlCatalog No: HY-P2847
CAS No: 330648-32-3
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor CRF2 receptor with Ki values of 0.66 nM and ?100 nM for CRFR2 and CRFR1, respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca2+/CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow.