GENERAL CATALOGUE
Urotensin-II receptor antagonist-1
HY-10672 · 50 mg
MedChemExpress · Cat: HY-10672
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medchemexpress.com/urotensin-ii-receptor-antagonist-1.html
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Catalog No: HY-10672
CAS No: 1034708-07-0
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
Urotensin-II receptor antagonist-1 compound 1 is a low oral bioavailability F=0-3 %, rat selective human Urotensin II receptor antagonist, Ki=16 nM test on HEK293 cells expressing recombinant human UT receptor . Urotensin-II receptor antagonist-1 inhibits cytochrome P450 IC50=0.75 ?M, CYP2D6; 1.4 ?M, CYP3A4 , inhibits ?-opioid receptor EC50=3.2 ?M , targets cardiac sodium channels Ki=2.5 ?M .
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