USP24 Rabbit Polyclonal Antibody

Description

EnkiLife offers the USP24 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: USP24; KIAA1057; Ubiquitin carboxyl-terminal hydrolase 24; Deubiquitinating enzyme 24; Ubiquitin thioesterase 24; Ubiquitin-specific-processing protease 24. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000 Background: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBA domain.,