GENERAL CATALOGUE
USP7-797
HY-136910 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-136910
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Catalog No: HY-136910
CAS No: 2413944-70-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
USP7-797 USP7-IN-7 is an orally available, selective USP7 inhibitor IC50=0.5 nmol/L with antitumor activity. USP7-797 reduces the level of MDM2, thereby increasing the stability and activity of p53, leading to cell cycle arrest and apoptosis. USP7-797 has low nanomolar cytotoxicity against p53 mutant cancer cell lines, p53 wild-type hematological tumors, and neuroblastoma cell lines.
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