GENERAL CATALOGUE
Utreloxastat
HY-132845 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-132845
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Catalog No: HY-132845
CAS No: 1213269-96-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Utreloxastat PTC857 is an orally active and blood-brain barrier-permeable 15-lipooxygenase inhibitor. Utreloxastat is a weak inhibitor of CYP1A2 and 2B6 with an IC50 of >5.3 ?M. Utreloxastat reduces oxidative stress and inhibits the consumption of reduced glutathione and ferroptosis. Utreloxastat can be used in the study of neurodegenerative diseases characterized by high levels of oxidative stress and mitochondrial pathology, such as amyotrophic lateral sclerosisc.
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