Valsartan methyl ester (Standard)

Description

Valsartan CGP 48933 methyl ester Standard is the analytical standard of Valsartan methyl ester HY-W414915 . This product is intended for research and analytical applications. Valsartan methyl ester is the methyl ester derivative of Valsartan HY-18204 . Valsartan is a selective angiotensin II type 1 AT1 receptor blocker ARB with potent antihypertensive and cardioprotective effects. Valsartan competitively binds to AT1 receptors, inhibiting the binding of angiotensin II to AT1 receptors, thereby blocking angiotensin II-mediated vasoconstriction, sodium retention, and myocardial hypertrophy signaling pathways. Valsartan reduces systolic blood pressure in L-NAME-induced hypertensive rats. Valsartan can be used for the study and treatment of arterial hypertension, hypertensive heart disease, and heart failure.