GENERAL CATALOGUE
VCC234718
HY-118061 · 1 mg
MedChemExpress · Cat: HY-118061
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medchemexpress.com/vcc234718.htmlCatalog No: HY-118061
CAS No: 1278553-16-4
Category: Anti-infection
Pack Size: 1 mg
Brand: MedChemExpress
Description
VCC234718 is a molecule with mycobacterial growth inhibitory activity, specifically targeting Mycobacterium tuberculosis Mtb . The primary molecular target of VCC234718 is inosine monophosphate dehydrogenase GuaB2 , and it inhibits the growth of Mtb by affecting the function of this enzyme. VCC234718 inhibits GuaB2 with a K value of 100 nM and exhibits non-competitive inhibition with IMP and NAD+. VCC234718 exerts its inhibitory effect by directly interacting with IMP and binding at the NAD+ site.
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