GENERAL CATALOGUE
VEGFR-2/AKT-IN-2
HY-169431 · 50 mg
MedChemExpress · Cat: HY-169431
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Manufacturer product page
medchemexpress.com/vegfr-2-akt-in-2.htmlCatalog No: HY-169431
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
VEGFR-2/AKT-IN-2 Compound 5 is a VEGFR-2/AKT inhibitor IC50: 0.061 ?M for VEGFRin HepG2 cell . VEGFR-2/AKT-IN-2 reduces total and phosphorylated AKT as well as up-regulates BAX and Caspase-3 and down-regulates Bcl-2 in cells, thereby promoting Apoptosis. VEGFR-2/AKT-IN-2 causes cell cycle arrest in S phase. VEGFR-2/AKT-IN-2 inhibits the growth of human liver tumor cells.