GENERAL CATALOGUE
VEGFR-2-IN-52
HY-161966 · 50 mg
MedChemExpress · Cat: HY-161966
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medchemexpress.com/vegfr-2-in-52.html
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Catalog No: HY-161966
CAS No: 3046428-94-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
VEGFR-2-IN-52 compound 14d is a potent VEGFR-2 inhibitor with an IC50 value of 191.1 nM. VEGFR-2-IN-52 decreases the protein expression of p-VEGFR-2, MMP9, p-ERK1/2 and p-MEK1. VEGFR-2-IN-52 shows cytotoxicity. VEGFR-2-IN-52 induces apoptosis and cell cycle arrest at G0/G1 phase. VEGFR-2-IN-52 increases the levels of ROS.
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