GENERAL CATALOGUE
VEN-02XX
HY-172941 · 5 mg
MedChemExpress · Cat: HY-172941
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Manufacturer product page
medchemexpress.com/ven-02xx.htmlCatalog No: HY-172941
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
VEN-02XX is an orally active and brain-permeable NLRP3 inhibitor. VEN-02XX inhibits the release of IL-1? and IL-18 IC50 0.3 and 0.28 ?M, respectively . VEN-02XX restores memory and cognition, inhibits microgliosis, and reduces neuroinflammation and tau pathology in the 5XFAD/Rubicon KO mouse model. VEN-02XX may be used in the study of Alzheimers disease AD .
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