GENERAL CATALOGUE
Vepafestinib
HY-132846 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-132846
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Manufacturer product page
medchemexpress.com/vepafestinib.htmlCatalog No: HY-132846
CAS No: 2129515-96-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Vepafestinib TAS0953/HM06 is a next-generation brain-penetrant, selective and orally active RET inhibitor with an IC50 value of 0.33 nM. Vepafestinib inhibits the phosphorylation of RET and its downstream signaling pathways, thus blocking the growth and signal transduction of tumor cells and inducing cell cycle arrest and apoptosis. Vepafestinib can be used in the research of various RET-driven cancers, such as non-small cell lung cancer, thyroid cancer and other disease areas.
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