GENERAL CATALOGUE
Verosudil
HY-16758 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-16758
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Catalog No: HY-16758
CAS No: 1414854-42-4
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Verosudil AR-12286 is a ROCK inhibitor. Verosudil has equal inhibitory activity against ROCK1 and ROCK2 Ki: 2 nM . Verosudil is less selective for PKA, PKCT, MRCKA, and CAM2A Ki: 69 nM, 9322 nM, 28 nM, 5855 nM, respectively . Verosudil increases trabecular outflow capacity to reduce intraocular pressure. Verosudil is useful in the study of glaucoma and ocular hypertension.
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