

HY-16758A · 50 mg
MedChemExpress · Cat: HY-16758A
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medchemexpress.com/verosudil-hydrochloride.htmlDescription
Verosudil AR-12286 hydrochloride is the hydrochloride form of Verosudil HY-16758 . Verosudil hydrochloride is a ROCK inhibitor. Verosudil hydrochloride has equal inhibitory activity against ROCK1 and ROCK2 Ki: 2 nM . Verosudil hydrochloride is less selective for PKA, PKCT, MRCKA, and CAM2A Ki: 69 nM, 9322 nM, 28 nM, 5855 nM, respectively . Verosudil hydrochloride increases trabecular outflow capacity to reduce intraocular pressure. Verosudil hydrochloride is useful in the study of glaucoma and ocular hypertension.