GENERAL CATALOGUE
Viloxazine
HY-W380450 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-W380450
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medchemexpress.com/viloxazine.htmlCatalog No: HY-W380450
CAS No: 46817-91-8
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Viloxazine is a non-brain-penetrant, selective norepinephrine transporter NET inhibitor IC50= 0.26 ?M and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors Ki=4.2 ?M and agonizes 5-HT2C receptors EC50= 32 ?M , respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder ADHD .
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