Vinculin Rabbit Monoclonal Antibody

Description

EnkiLife offers the Vinculin Rabbit Monoclonal Antibody. This antibody reacts with Human, Mouse, Rat species and is suitable for WB application. Alternative Names of Immunogen: VCL; Vinculin; Metavinculin. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration. Research Area: Signal Transduction