

HY-155971 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-155971
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medchemexpress.com/vista-in-2.htmlDescription
VISTA-IN-2 Compound 1 is an inhibitor of V-domain Ig suppressor of T-cell activation VISTA . VISTA-IN-2 induces VISTA degradation in cells through an autophagic mechanism. VISTA-IN-2 rescues VISTA-mediated immunosuppression, and enhances antitumor activity of immune cells. VISTA-IN-2 also activates the antitumor immunity and inhibits tumor growth in a CT26 mouse model.







