GENERAL CATALOGUE
Volasertib (Standard)
HY-12137R · 5 mg
MedChemExpress · Cat: HY-12137R
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medchemexpress.com/volasertib-standard.html
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Catalog No: HY-12137R
CAS No: 755038-65-4
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Volasertib Standard is the analytical standard of Volasertib. This product is intended for research and analytical applications. Volasertib BI 6727 is an orally active, highly potent and ATP-competitive Polo-like kinase 1 PLK1 inhibitor with an IC50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models.
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