

HY-100007 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-100007
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Manufacturer product page
medchemexpress.com/TAK-438-free-base.html
Description
Vonoprazan TAK-438 free base , a proton pump inhibitor PPI , is a potent and orally active potassium-competitive acid blocker P-CAB , with antisecretory activity. Vonoprazan inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori.







