GENERAL CATALOGUE
Vorbipiprant
HY-156649 · 5 mg
MedChemExpress · Cat: HY-156649
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Catalog No: HY-156649
CAS No: 1417742-86-9
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
Vorbipiprant CR6086 is an orally active EP4 receptor antagonist with high selectivity for the human EP4 receptor Ki: 16.6 nM . Vorbipiprant has immunomodulatory, anti-inflammatory, antitumor, and anti-angiogenic activities. Vorbipiprant can inhibit the expression of multiple pro-inflammatory cytokines and the activation of immune cells, and convert cold tumors unresponsive to immune checkpoint inhibitors into hot tumors. Vorbipiprant is used in the research of diseases such as rheumatoid arthritis and colon cancer.
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