

HY-128879A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-128879A
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medchemexpress.com/vp3-15-dihydrobromide.htmlDescription
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase PDE 7- glycogen synthase kinase GSK 3 inhibitor, with IC50s of 1.59 ?M and 0.88 ?M for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis MS .







