GENERAL CATALOGUE
VPM-p15
HY-P10365 · 5 mg
MedChemExpress · Cat: HY-P10365
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Catalog No: HY-P10365
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
Vmm-p15 is a peptide agonist optimized for the adhesion G protein-coupled receptor GPR64 also known as ADGRG2 or HE6 . The affinity of VPM-p15 with GPR64 is significantly higher than that of the original p15 peptide. The cAMP level induced by VMM-P15 increased significantly, activated GPR64, and triggered downstream Gs, Gq, and G12/13 signaling. VPM-p15 can be used to study the activation mechanism of adherent GPCR family members.
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