GENERAL CATALOGUE
Vps34-IN-1
HY-12795 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-12795
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medchemexpress.com/Vps34-IN-1.htmlCatalog No: HY-12795
CAS No: 1383716-33-3
Category: Autophagy
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Vps34-IN-1 is a potent and selective inhibitor of class III Vps34 PI3K. Vps34-IN-1 inhibits phosphorylation of PtdIns by recombinant insect cell expressed Vps34-Vps15 complex with an IC50 of 25 nM. Vps34-IN-1 can suppress SGK3 activation by reducing PtdIns 3 P levels via lowering phosphorylation of T-loop and hydrophobic motifs. Vps34-IN-1 modulates autophagy.
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