GENERAL CATALOGUE
VSLRGDTRG acetate
HY-P10941A · 1 mg
MedChemExpress · Cat: HY-P10941A
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medchemexpress.com/vslrgdtrg-acetate.html
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Catalog No: HY-P10941A
Category: Cytoskeleton
Pack Size: 1 mg
Brand: MedChemExpress
Description
VSLRGDTRG acetate is a synthetic peptide containing the RGD motif from cadherin 17 CDH17 , which binds to ?2?1 integrin and activates its signaling pathway. VSLRGDTRG acetate promotes the high-affinity conformational change of ?1 integrin through the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. VSLRGDTRG acetate can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer.