GENERAL CATALOGUE
VTX-0811
HY-P991432 · 1 mg
MedChemExpress · Cat: HY-P991432
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medchemexpress.com/vtx-0811.html
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Catalog No: HY-P991432
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
VTX-0811 is a human IgG4 monoclonal antibody mAb targeting PSGL1/CD162. VTX-0811 up-regulates TNF-?/NF-?B and chemokine-mediated signaling and down-regulates oxidative phosphorylation, fatty acid metabolism, and Myc signaling pathways. VTX-0811 increases the proportion of CD8+ T cells among infiltrating T cells. VTX-0811 has antitumor activity in a humanized mouse PDX model of melanoma.
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